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Congential heart disease affects approximately one percent of all children born worldwide. This multidisciplinary project will combine novel 3D imaging, using synchrotron-based phase contrast micro-CT, with cell and molecular biology for improved understanding of congenital heart defects and cardiovascular function. The primary focus will be the importance of basement membranes for cardiovascular

https://www.wcmm.lu.se/importance-basement-membranes-cardiovascular-development-and-disease - 2025-10-29

Purpose | Our study seeks to contribute novel insights into the development of novel HSC-based regenerative strategies for multiple sclerosis (MS) using our recently defined connection point between peripheral and-CNS immunity. We aim to develop a better mechanistic understanding of this autologous cell therapy, keeping clinical translation in mind, thereby offering new hope for individuals affect

https://www.wcmm.lu.se/autologous-bone-marrow-transplantation-treatment-multiple-sclerosis-endogenous-hematopoietic-stem - 2025-10-29

The Stars of the Brain Iben Lundgaard, Associate Professor | LUNDGAARD LAB Through Synchrotron Eyes: A Glimpse into Early Heart Development Niccolò Peruzzi, Postdoc | TRAN LUNDMARK LAB Alpha Synuclein Galaxy Oksana Tymoshchuk, Research Associate | LUNDGAARD LAB Shortcut Karin Tran Lundmark, Principal Investigator | TRAN LUNDMARK LAB Developing Chick Embryo Nika Gvazava, PhD student | WAGNER LAB Au

https://www.wcmm.lu.se/whats/wcmm-fusion-2025-where-science-meets-art/where-science-meets-art - 2025-10-29

Back to news archiveTandem researchers Smith & MeissnerRead about Gustav Smith and Anja Meissner in LUM magasin nr 6, 2017 .

https://www.wcmm.lu.se/tandem-researchers-smith-meissner - 2025-10-29

Back to news archiveThe calls for our first two tenure track research positions (Associate Senior Lecture level) within WCMM LU are now closed as of February 1st 2016.We are happy to announce a large interest of applicants for the two positions Molecular Medicine: Regeneration and repair in the nervous system and Molecular Medicine: Regeneration and repair in the cardiovascular system, respectivel

https://www.wcmm.lu.se/first-call-tenure-track-positions-closed - 2025-10-29

Nika Gvazava, PhD student | WAGNER LAB The storyTissue clearing is a ground breaking technique that has transformed our ability to image complex biological structures in 3D, including visualization of intricate cellular architectures in their native environment with high spatial resolution. It involves selectively reducing the amount of light-scattering and absorption molecules (e.g lipids) from b

https://www.wcmm.lu.se/developing-chick-embryo - 2025-10-29

Iben Lundgaard, Associate Professor | LUNDGAARD LAB The storyThis image shows astrocytes contacting and wrapping themselves around cerebral blood vessels in the pig brain.Research areaThe glymphatic brain clearance system, which we believe is important for preventing development of diseases, such as Alzheimer’s disease.Image descriptionAstrocytes, glia cells, in light blue and blood vessels in mul

https://www.wcmm.lu.se/stars-brain-0 - 2025-10-29

Oksana Tymoshchuk, Research Associate | LUNDGAARD LAB The storyThis was an experiment with chronic fibrils, during which we bilaterally injected fibrils into the brains of mice and observed these mice over a period of six months. The image was taken six months after the fibril injection. It was a collaborative project with universities in the United States. Together, we are taking small steps towa

https://www.wcmm.lu.se/alpha-synuclein-galaxy - 2025-10-29

Back to news archiveResearchers at Lund University and Region Skåne are invited to submit Letters of Intent to LU WCMM regarding topics for new tenure track positions. The submission deadline is Monday, March 21 24.00. For all information, please see the link below:

https://www.wcmm.lu.se/invitation-submit-letters-intent - 2025-10-29

Bryan Falcones, Postdoc | WESTERGREN THORSSON LAB The storyHidden within the intricate architecture of lung tissue lies a chemical mosaic, a story told by the distribution of elements that govern health and disease. Using the X-ray imaging capabilities at MAX IV laboratory, researchers have illuminated this unseen world with unprecedented detail. At the heart of this process is the synchrotron, a

https://www.wcmm.lu.se/elemental-breath-chemical-mosaic-lung-tissue - 2025-10-29

Poojaswini Thimmaraya Reddy, MSc student | CONSIGLIO LAB The storyThe story I want to tell with this art piece is about the complex and varied immune profiles of different women, focusing on the differences in their cytokine levels in serum and follicular fluid. Cytokines are crucial signaling molecules in the immune system that play a key role in inflammation, immune response, and tissue repair.

https://www.wcmm.lu.se/cytokine-heatmap - 2025-10-29

Kelley Swanberg, Postdoc | LUNDGAARD LAB The storyAn intricate web of disparate experimental, signal acquisition, processing and analysis methods within in vivo proton magnetic resonance spectroscopy converges beautifully to depict the cortical metabolic similarities between two distinct species.Research areaThe glymphatic brain clearance system, in vivo functional and metabolic signatures of glym

https://www.wcmm.lu.se/symmetry - 2025-10-29

João Duarte, Associate Professor | DUARTE LAB The storyThis artwork celebrates the wonder and mystery of the microscopic world. A neuron stained for the enzyme hormone-sensitive lipase (HSL) glows like a celestial body in the vast expanse of the cell dish. The bright hues and intricate details highlight the presence of HSL throughout the neuron and in its in dendritic spines, where it interfaces l

https://www.wcmm.lu.se/glow-hls-celestial-neurons - 2025-10-29

Back to news archiveLund University and Skåne University Hospital hereby announce two clinical research positions within the Wallenberg Centre for Molecular Medicine at Lund University (WCMM LU).As part of the first call within the WCMM LU, one combined clinical/research position in each of the fields of: 1) Regeneration and repair in the nervous system and 2) Regeneration and repair in the cardio

https://www.wcmm.lu.se/two-50-clinical-research-positions-within-wcmm-lu - 2025-10-29

Oscar van der Have, PhD student | TRAN LUNDMARK LAB The storyWe aim to highlight the vast possibilities that lie hidden in paraffin-embedded biobank tissue samples, through the utilization of new imaging modalities and computer-assisted reconstructions. In this image, we have integrated four types of histological analysis of the same tissue sample – from traditional to cutting-edge – into a single

https://www.wcmm.lu.se/embedded - 2025-10-29

Karin Tran Lundmark, Principal Investigator | TRAN LUNDMARK LAB The storyMost things in this world tends to take the easy way out if possible. This includes the blood in the lung.Research areaPulmonary vascular biology.ImpactThis type of imaging can teach us about the 3D structure of different types of diseases. When combined with other methods it becomes a powerful tool for exploring disease mech

https://www.wcmm.lu.se/shortcut - 2025-10-29

Niccolò Peruzzi, Postdoc | TRAN LUNDMARK LAB The storyThis piece showcases how synchrotron imaging can reveal the hidden processes that sustain life at its earliest stages. This rendering of a fetal mouse heart portrayed as if crafted from transparent glass, invites viewers to glimpse the delicate yet complex nature of life as it forms. Within this fragile structure lies a vibrant, solid red netwo

https://www.wcmm.lu.se/through-synchrotron-eyes-glimpse-early-heart-development - 2025-10-29

Joan Escrivà Font, PhD student | CONSIGLIO LAB The storyImmune responses vary across individuals. This huge diversity can be measured and summarized to a few estimates that are visualized in aesthetically displeasing plots. One can also use more engaging representations like epitrochoids, which are  typically drawn with Spirographs. Here, we were interested in understanding how feminizing hormone

https://www.wcmm.lu.se/drawing-immunity-dynamics-epitrochoid-patterns-hormone-modulated-responses - 2025-10-29

Julia Martinez, PhD student | SMITH LAB The storyMy research focuses on the giant sarcomeric protein Titin, crucial for heart elasticity. While its striated structure is well-known, imaging heart cells revealed its striking clarity. Our current study examines a smaller Titin isoform, Novex-3, which is upregulated in heart failure tissue compared to donor hearts. Novex-3’s location and function in

https://www.wcmm.lu.se/titin-spiderweb-heart-mysterious-protein-novex-3 - 2025-10-29

Carolina Buizza, PhD student | PAUL-VISSE LAB The storySince beginning my PhD, I’ve carried out countless immunohistochemical experiments. Many weekends have been spent washing and mounting brain sections onto thin glass slides, and countless hours passed in a dark room at the microscope—even on those rare sunny days. Disclaimer: most of these experiments haven’t worked out. Sometimes it’s a fault

https://www.wcmm.lu.se/blood-vessels-tumors-silent-climb - 2025-10-29